A drug that mimics EPO as a way to help patients with kidney problems is in the late stages of development, one in an long list of new pharmaceuticals that anti-doping authorities are monitoring as they struggle to keep sports clean.
The drug, called Hematide, is in Stage 3 development, meaning it could be on the market by 2012. Anti-doping authorities say there's a chance some version of the blood-boosting drug could already be available on the black market.
"It speaks to the length people will go to try to cheat," said Larry Bowers, the lead scientist at the U.S. Anti-Doping Agency. "You get drugs with perfectly beneficial health purposes and it gets diverted for use by people who shouldn't be doing it."
Almost every drug on the World Anti-Doping Agency's banned list, including human growth hormone and steroids, have legitimate medical purposes.
Hematide's arrival is the latest development in a long-running cat-and-mouse game between the drug police and the athletes who find ways to use drugs to improve their performance. Cases involving track athletes Marion Jones, baseball players Barry Bonds and Roger Clemens and an investigation into seven-time Tour de France winner Lance Armstrong have centered around whether they used human growth hormone, EPO or designer steroids, all of which have proven more difficult to detect than traditional steroids.
Before Hematide, the most significant development in the line of EPO products was CERA, a version of EPO that stays in the blood for longer periods of time. There was no test available for CERA at the Beijing Olympics, but the International Olympic Committee holds onto doping samples for eight years so it can analyze them later if new testing methods become available.
Using a new test in 2009 is how the IOC retroactively caught five Beijing Olympians for using CERA. This year, the IOC said it was retesting some samples from the 2006 Turin Olympics — strong indicators of how patient anti-doping authorities are willing to be to catch cheaters.
One of the newer drugs on WADA's radar, Hematide essentially does the same thing as EPO — helps produce more red blood cells — but, much like CERA, it stays in the body longer so patients don't have to go through as many treatments.
Still, Hematide is not EPO, and so it must be detected using different methods than were used for the original blood booster. Anti-doping authorities are strategically vague when talking about whether a test is already in place for developing drugs, not wanting drug cheats to know what solutions have been found or perfected. At an anti-doping conference last year, WADA said it was studying a new method that would allow wider testing of EPO.
And in yet another attempt to counter possible new EPO-like substances — as well as all other developing drugs that haven't hit the market yet — WADA recently added a category of "non-approved substances" that covers developing products that are not included in other sections of the list and not yet approved for use.
Hematide, however, is already specifically named on the banned list, said Gary Wadler who leads the WADA committee that determines the banned-substances list.
Earlier this year, WADA signed an agreement with a group representing pharmaceutical companies that gets the companies to voluntarily share information with drug police when they're developing new products. It was considered a breakthrough, giving anti-doping authorities a window into what's out there. In return, WADA has to agree not to share proprietary information between competing companies.
"The mission is to be good citizens here," said Anne-Marie Duliege, chief medical officer at Affymax, the company developing Hematide. "We clear it with the professional agencies who know how to do this. The idea is not to replace WADA. We're just delighted to work with WADA, so they can see what's out there and what they might need to prevent down the road."
It's too early to tell how big a factor Hematide might be on the doping scene, though clearly, the effort to detect it is well underway more than a year before its expected arrival to the market.
"We work with the people involved with it. It's not like it came out of nowhere," Wadler said. "We all follow the literature on what's being developed. Something like this does not surprise you at all."
Showing posts with label oxandrolone. Show all posts
Showing posts with label oxandrolone. Show all posts
More details on the UK's plan to ban personal use steroid imports.
The government's expert drug advisers are pressing for a ban on online imports of anabolic steroids amid growing concern over their use by teenage boys and young men to improve their body image.
The Advisory Council on the Misuse of Drugs (ACMD) says the ban is needed because the steroids sold online are often contaminated, out of date, or delivered with the wrong dosage instructions.
The ACMD's chair, Professor Leslie Iversen, said steroids were now much too easily available: "If you search online you will see endless offers. The ACMD is the lone voice against this tide of promotion on the internet. We think [an import ban] would have a considerable dampening effect on demand. It may be difficult to enforce but it would act as a simple deterrent."
Iversen said steroids were becoming a "big phenomenon" in Britain: "There is no question that the number using the drug for sporting reasons is now a minority. The real growth has come in young users who want to improve their body image."
An ACMD report to the home secretary on anabolic steroids published today quotes the latest figures from the British Crime Survey, estimating that 50,000 people in the past year have used anabolic steroids for non-medical purposes, such as bodybuilding. More than 220,000 told the BCS they had used anabolic steroids.
But drug experts say these are probably underestimates of the numbers using anabolic steroids because many people will not openly admit to using the drugs, even in an anonymous self-report survey such as the BCS. Some needle and syringe exchange programmes for problem drug users have also reported an exponential rise in steroid injectors, according to the report.
Iversen said the rising use of anabolic steroids, particularly among young men, was a worrying development: "While the health-related harms associated with these substances are not as severe as with some other drugs, misuse carries significant risks, particularly for young people whose bodies are still developing. More needs to be done to tackle the supply of anabolic steroids and to educate people to the potential dangers."
The report says most of the harmful effects of anabolic steroids are not life-threatening and only a small number of deaths have ever been attributed to liver damage associated with long-term steroid use. However, it raises distinct concerns about their use by young people saying they can potentially disrupt the normal pattern of physical growth and induce masculinising effects in women and children.
Anabolic steroids have been used since the 1950s by bodybuilders and weightlifters to build muscle as well as by elite athletes to improve their performance. The use of steroids is now widely banned by the sporting authorities.
The ACMD says anabolic steroids should remain a class C illegal drug, which can be bought on prescription from a pharmacist. While it is illegal to import or sell steroids for non-medical purposes it is currently legal to possess or import steroids as long as they are for personal use only.
The drug advisory body says it is now time to make it illegal to order substances online from overseas websites and import them by post or courier. Personal possession, including bringing them into the country, will however remain legal as the authorities believe criminalising users would simply push the problem underground.
The drugs minister, James Brokenshire, said steroids were dangerous substances which could cause serious psychiatric and physical problems: "We will carefully review the recommendations set out in this report and respond shortly."
The Advisory Council on the Misuse of Drugs (ACMD) says the ban is needed because the steroids sold online are often contaminated, out of date, or delivered with the wrong dosage instructions.
The ACMD's chair, Professor Leslie Iversen, said steroids were now much too easily available: "If you search online you will see endless offers. The ACMD is the lone voice against this tide of promotion on the internet. We think [an import ban] would have a considerable dampening effect on demand. It may be difficult to enforce but it would act as a simple deterrent."
Iversen said steroids were becoming a "big phenomenon" in Britain: "There is no question that the number using the drug for sporting reasons is now a minority. The real growth has come in young users who want to improve their body image."
An ACMD report to the home secretary on anabolic steroids published today quotes the latest figures from the British Crime Survey, estimating that 50,000 people in the past year have used anabolic steroids for non-medical purposes, such as bodybuilding. More than 220,000 told the BCS they had used anabolic steroids.
But drug experts say these are probably underestimates of the numbers using anabolic steroids because many people will not openly admit to using the drugs, even in an anonymous self-report survey such as the BCS. Some needle and syringe exchange programmes for problem drug users have also reported an exponential rise in steroid injectors, according to the report.
Iversen said the rising use of anabolic steroids, particularly among young men, was a worrying development: "While the health-related harms associated with these substances are not as severe as with some other drugs, misuse carries significant risks, particularly for young people whose bodies are still developing. More needs to be done to tackle the supply of anabolic steroids and to educate people to the potential dangers."
The report says most of the harmful effects of anabolic steroids are not life-threatening and only a small number of deaths have ever been attributed to liver damage associated with long-term steroid use. However, it raises distinct concerns about their use by young people saying they can potentially disrupt the normal pattern of physical growth and induce masculinising effects in women and children.
Anabolic steroids have been used since the 1950s by bodybuilders and weightlifters to build muscle as well as by elite athletes to improve their performance. The use of steroids is now widely banned by the sporting authorities.
The ACMD says anabolic steroids should remain a class C illegal drug, which can be bought on prescription from a pharmacist. While it is illegal to import or sell steroids for non-medical purposes it is currently legal to possess or import steroids as long as they are for personal use only.
The drug advisory body says it is now time to make it illegal to order substances online from overseas websites and import them by post or courier. Personal possession, including bringing them into the country, will however remain legal as the authorities believe criminalising users would simply push the problem underground.
The drugs minister, James Brokenshire, said steroids were dangerous substances which could cause serious psychiatric and physical problems: "We will carefully review the recommendations set out in this report and respond shortly."
Undercover operation finds several Australian Police on the Gold Coast using steroids.
An undercover operation discovered six Gold Coast police officers were using anabolic steroids for "no good medical reason", an anti-corruption inquiry has heard.
A Crime and Misconduct Commission (CMC) public hearing today was told the officers, mainly from the Surfers Paradise station, had been prescribed steroids even though they weren't suffering from any disease or medical problem which required them.
The CMC hearing follows the watchdog's Operation Tesco which investigated allegations of police misconduct, including that some officers had associated with criminals, engaged in drug use and misused confidential police information.
The evidence of steroid use followed testimony yesterday from the Gold Coast's senior officer Superintendent Jim Keogh that he had suspicions some young male officers on the holiday strip may be using such drugs.
Counsel assisting the commission John Allen said none of the officers were suffering any disease or medical condition that would justify the drugs.
"These officers were healthy - they gave varied reasons for needing the steroids including feeling tired, lethargic or just wanting to be bigger," Mr Allen said.
"Each sought this treatment from the same doctor who was prepared to assist the."
Mr Allen also told the hearing a professor who specialised in the effects of steroids had told the CMC people abusing the drugs had a tendency to use high doses of them, topping them up with black market product.
"They can get anxious, have sleep difficulties, become agitated, irritable, angry, can over-react to situations and their judgment may not be as balanced as it might usually be," he said.
Mr Allen said that could be of obvious concern if the person abusing steroids was an armed police officer.
A Crime and Misconduct Commission (CMC) public hearing today was told the officers, mainly from the Surfers Paradise station, had been prescribed steroids even though they weren't suffering from any disease or medical problem which required them.
The CMC hearing follows the watchdog's Operation Tesco which investigated allegations of police misconduct, including that some officers had associated with criminals, engaged in drug use and misused confidential police information.
The evidence of steroid use followed testimony yesterday from the Gold Coast's senior officer Superintendent Jim Keogh that he had suspicions some young male officers on the holiday strip may be using such drugs.
Counsel assisting the commission John Allen said none of the officers were suffering any disease or medical condition that would justify the drugs.
"These officers were healthy - they gave varied reasons for needing the steroids including feeling tired, lethargic or just wanting to be bigger," Mr Allen said.
"Each sought this treatment from the same doctor who was prepared to assist the."
Mr Allen also told the hearing a professor who specialised in the effects of steroids had told the CMC people abusing the drugs had a tendency to use high doses of them, topping them up with black market product.
"They can get anxious, have sleep difficulties, become agitated, irritable, angry, can over-react to situations and their judgment may not be as balanced as it might usually be," he said.
Mr Allen said that could be of obvious concern if the person abusing steroids was an armed police officer.
Pakistani runner Zahoor gets 2 year steroids ban.
Pakistan has suspended former Olympic runner Sumaira Zahoor for two years after she tested positive for steroids. Sports ministry spokesman Faik Ali said the 30-year-old Zahoor was given the suspension after appearing before a three-member committee of the national anti-doping body on Monday. Committee member Khalid Mehmood said Zahoor could appeal the ban. Zahoor competed in the 2004 Athens Olympics, but failed to advance out of her heat in the 1,500 meters. Pakistan will not compete in any of the track and field events at next month's Commonwealth Games in New Delhi.
Police officer loses his Anavar and ends up getting a two week suspension.
A police officer agreed to an unpaid 15-day suspension after he didn’t properly notify police that 200 pills were missing from his patrol car when he picked up the vehicle from a city contractor, according to recently released records and a lieutenant.
Officer Jedadiah Cotterman agreed to the suspension that ended an internal affairs inquiry focusing on Cotterman’s alleged handling of a June incident that happened when he dropped his patrol vehicle off at Atlantic Collision on Southwest South Macedo Boulevard.
When Cotterman returned to get the vehicle several days later, he noticed two bags containing 200 tablets missing. An Atlantic employee said Cotterman said the medication was “for his liver and if he doesn’t take the medications, his eyes turn yellow,” records show.
The Atlantic employee said the employees are trustworthy and thought the medication inadvertently was thrown out or swept up. The employee offered to reimburse Cotterman even though it wasn’t the business’ standard practice to do so. He gave Cotterman a check for $300.
The Atlantic employee called another officer to explain the situation, and the other officer eventually said an officer would be coming to take a report.
The officer who met Cotterman said Cotterman was “reluctant” to say what the medication was for, saying he was “embarrassed.” He ultimately said it was a steroids he used for weight loss. Cotterman said the medicine was “Oxandrolone” and that he didn’t need a prescription for it. The pills also reportedly “went by the brand name ‘Anavar.’”
The officer did an Internet search and found the medicine did require a prescription.
The officer said he thought Cotterman “was not being truthful about not needing a prescription for the reported missing medication.”
Police spoke with a friend of Cotterman’s who said he sold Cotterman the tablets. The friend described himself as a “supplement meathead” who spends lots of money on protein, testosterone boosters, fat burners and other things. The friend said he sold Cotterman two bottles of “Anavar,” which he said are a “legal, over-the-counter supplement.”
The Anavar cost him $50 per bottle and he sold the two bottles to Cotterman for $100.
He said Cotterman gave him $300 for the “Anavar,” though he said he added $200 to Cotterman’s bill for repayment of a loan he gave Cotterman.
He said “maybe” Cotterman thought he was selling each “Anavar” bottle for $150.
The friend said he told Cotterman that “Anavar” was known as a “fat burner” that promoted weight loss.
Police returned the $300 check to Atlantic Collision.
Lt. Ron Caudell on Monday said investigators had no pills to test to determine exactly what Cotterman had. He said the improper conduct stemmed from Cotterman not properly reporting the steroids that were missing from his patrol car.
Police records show the State Attorney’s Office declined to prosecute because of a lack of physical evidence and also because no witnesses could say Oxandrolone was in Cotterman’s possession.
Officer Jedadiah Cotterman agreed to the suspension that ended an internal affairs inquiry focusing on Cotterman’s alleged handling of a June incident that happened when he dropped his patrol vehicle off at Atlantic Collision on Southwest South Macedo Boulevard.
When Cotterman returned to get the vehicle several days later, he noticed two bags containing 200 tablets missing. An Atlantic employee said Cotterman said the medication was “for his liver and if he doesn’t take the medications, his eyes turn yellow,” records show.
The Atlantic employee said the employees are trustworthy and thought the medication inadvertently was thrown out or swept up. The employee offered to reimburse Cotterman even though it wasn’t the business’ standard practice to do so. He gave Cotterman a check for $300.
The Atlantic employee called another officer to explain the situation, and the other officer eventually said an officer would be coming to take a report.
The officer who met Cotterman said Cotterman was “reluctant” to say what the medication was for, saying he was “embarrassed.” He ultimately said it was a steroids he used for weight loss. Cotterman said the medicine was “Oxandrolone” and that he didn’t need a prescription for it. The pills also reportedly “went by the brand name ‘Anavar.’”
The officer did an Internet search and found the medicine did require a prescription.
The officer said he thought Cotterman “was not being truthful about not needing a prescription for the reported missing medication.”
Police spoke with a friend of Cotterman’s who said he sold Cotterman the tablets. The friend described himself as a “supplement meathead” who spends lots of money on protein, testosterone boosters, fat burners and other things. The friend said he sold Cotterman two bottles of “Anavar,” which he said are a “legal, over-the-counter supplement.”
The Anavar cost him $50 per bottle and he sold the two bottles to Cotterman for $100.
He said Cotterman gave him $300 for the “Anavar,” though he said he added $200 to Cotterman’s bill for repayment of a loan he gave Cotterman.
He said “maybe” Cotterman thought he was selling each “Anavar” bottle for $150.
The friend said he told Cotterman that “Anavar” was known as a “fat burner” that promoted weight loss.
Police returned the $300 check to Atlantic Collision.
Lt. Ron Caudell on Monday said investigators had no pills to test to determine exactly what Cotterman had. He said the improper conduct stemmed from Cotterman not properly reporting the steroids that were missing from his patrol car.
Police records show the State Attorney’s Office declined to prosecute because of a lack of physical evidence and also because no witnesses could say Oxandrolone was in Cotterman’s possession.
Sciroxx label preview - some proof reading needed :-)
Very nice graphic design on these, the horizontal labels I presume are for use on tubs, the longer ones for their orals packaged in pouches.
Thai brands of Oxandrolone tabs.
I've been looking for a new brand of oxandrolone tab to try. The two obvious choices were the locally produced SB Labs "OxanSB" and LaPharma Oxandrolone products.
The LaPharma product despite having approx the same cost per bottle works out far less economical as it contains just 30 * 10mg tabs vs 50 * 10mg for the SB Labs version.
I'm assuming of course that both brands are fully dosed products.
I was impressed by the embossed bottle lids but I'm a little sad that they both use labels that appear to be printed on desktop ink jets. Surprising really as professional printing in Asia is cheap and usually "no questions asked".
I'm hoping someone will lab test both products soon, if anyone knows of a current public testing lab please drop me a line.
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