Study finds blocking androgen receptors speeds up wound healing.

A molecular receptor vital to the functioning of male hormone testosterone also plays a key role in healing.

In mice studies, University of Rochester Medical Centre (URMC) scientists found that this receptor, the androgen receptor, delays wound healing. However, when they blocked the receptor with an experimental compound, wounds healed much more quickly.


“Turning off the androgen receptor only where you want to, and nowhere else, could lead to new treatments for diseases like prostate cancer and for speeding wound healing,” said Edward Messing, urologist and surgeon at the URMC, not involved in the study.


“Currently there is no way of preventing androgens in your body from reaching just one particular wound or one specific part of the body,” said Messing.


“To stop them anywhere, you need to turn off androgens throughout the body, which has severe and unpleasant side effects, particularly in men,” added Messing.

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