"Restricting sleep to under six hours a night along with sedentary living affects glucose tolerance and insulin sensitivity, possibly increasing the risk of developing type 2 diabetes, according to a study published online June 30 in the Journal of Clinical Endocrinology & Metabolism.
Arlet V. Nedeltcheva, M.D., and colleagues from the University of Chicago examined whether restricted sleep (5.5 hours versus 8.5 hours per night) and sedentary living over two 14-day periods affected glucose tolerance and insulin secretion and action in 11 healthy middle-aged adults.
The researchers found that while weight gain was similar over both periods, restricting sleep to 5.5 hours a night significantly reduced oral glucose tolerance and insulin sensitivity and significantly increased glucose effectiveness. Sleep restriction was not associated with changes in 24-hour cortisol and growth hormone concentrations, but there was a small increase in 24-hour epinephrine and night-time norepinephrine levels.
"Experimental bedtime restriction, designed to approximate the short sleep times experienced by many individuals in Westernized societies, may facilitate the development of insulin resistance and reduced glucose tolerance," Nedeltcheva and colleagues conclude."
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